Effect of Indication Based Blood Product Transfusion in Patients Undergoing Major Oncological Surgery

Sex: All

Ages: 18 Years – 70 Years

Phase: PHASE2, PHASE3

Enrollment: 260

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Summary

Investigators aimed to compare the effect on different indications (blood volume loss based VS hemoglobin concentration based ) based blood transfusion practices in patients undergoing major oncological surgery for pelvic or spinal tumor and investigate their postoperative complications.

Eligibility Criteria

Inclusion Criteria:age between 18 and 70patients with pelvic or spinal tumorconduct open resection surgery for tumor removalwith expected surgery duration greater than 3 hourswith expected blood loss greater than 400 mlExclusion Criteria:age < 18 or >70Limb tumor patients or patients with pelvic and spinal tumors undergoing closed internal fixation or vertebroplasty or minimally invasive surgeryreceived chemotherapy or immunotherapy before surgerywith expected surgery length less than 3 hourswith expected intraoperative blood loss less than 400ml

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05607940). StuddyBuddy aggregates publicly available trial information.