Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy

Out of 30,000 new cases per year in France, 30% of epileptic patients are drug-resistant. Neurosurgery, which consists in resecting the epileptogenic zone, is the only chance of cure. In the case of temporal epilepsy of the language-dominant hemisphere (TLE), this procedure presents a high risk of increasing cognitive difficulties and may even be contraindicated for this reason alone. The difficulties found are impairments in lexical access (anomia) and verbal memory and affect more than 60% of patients . Preoperative cognitive rehabilitation could influence brain plasticity mechanisms but there are currently no recommendations on this topic. In this context, the investigators have developed a speech rehabilitation procedure specific to the needs of ELTPR patients. They rely on cognitive hypotheses explaining the disorders but also on models of rehabilitation-induced neural plasticity likely to improve cognitive reserve before surgery. The investigators hypothesize that preoperative cognitive language rehabilitation in ELTPR patients may decrease surgical risk and improve postoperative language prognosis.The primary objective is to demonstrate the protective efficacy of preoperative speech rehabilitation on language performance postoperatively.

Inclusion Criteria:Patient 16 years of age or older,Patient who has signed an informed consent or patient whose parents or legal guardians have signed the informed consent (or a single parent or legal guardian if applicable)Patient whose epileptogenic zone involves the temporal structures of the hemisphere specialized for language,Patient whose hemispheric specialization for language is known by fMRI (performed as part of care),Patient willing to undergo resective surgery such as anterior temporal lobectomy and whose planned surgery date is compatible with the study,Patient whose mother tongue is French (1st language learned by the patient),Patient declaring to be familiar with the use of a computer and having access to an internet connection from homePatient with a known NTB scorePatient affiliated or benefiting from a social security plan.Exclusion Criteria:Pregnant, breastfeeding, deprived of liberty, under guardianship or curatorship;Patients with speech disorders that may impair intelligibility and compromise the use of the interface;Patient with an uncorrected hearing impairment,Patient with a total intelligence quotient (IQ) <70 (evaluated in the context of care, in the year preceding the surgical procedure)