Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI

The goal of this observational study is to evaluate the complimentary information of anatomy, perfusion and viability of PET and MR. The main question[s] it aims to answer are:to compare perfusion and anatomy measurements and perfusion related signals from PET and MR imaging and estimate its prognostic values.to evaluate potential optimization of routine scanning procedure with re-gards to completeness and potential added value of quantitative measurements.

Inclusion Criteria:Male and Female participants over the age of 18 yearsWritten informed consent by the participant after information about the research projectSymptoms consistent with possible coronary artery diseaseClinical referral for a vasodilator stress CMR and/or PET exami-nationExclusion Criteria:Patients with high degree heart blockContraindications to gadolinium-enhanced CMR examinationSevere claustrophobiaSpecific implantable devices which are contraindicated for CMRCurrent pregnancyAdvanced renal disease (GFR<30)Uncontrolled obstructive pulmonary disease or asthmaAtrial fibrillation at the time of study enrolment