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Completed
NCT05609721
Mild Traumatic Brain Injury and the Risk for Traumatic Intracranial Hemorrhage
Conditions: Traumatic Intracranial Hemorrhage, Brain Injuries
Enrollment: 2044
Sponsor: Umeå University
Location: Sweden
Summary
Management of traumatic brain injuries causes significant efforts on emergency departments (ED) and overall health care.
Patients on antithrombotic treatment with even minor trauma to the head, although without significant clinical findings, represent special challenges because the risk of traumatic intracranial hemorrhage (tICH) with these agents.
The aim of this study was to compare the prevalence of tICH in patients on various pre-injury antithrombotic treatment exposed to minor Traumatic Brain injuries (mTBI) in Sundsvall with untreated patients.
Secondary aim was to explore different risk factors for tICH.Data from medical records and radiology registry with mTBI in Sundsvall hospital between 2018-2020 in Sundsvall identified 2044 patients.
Demographic data, pre-injury medications with antithrombotic treatment, state of consciousness at admission and the results of CT-scans of brain was investigated.
Eligibility Criteria
Inclusion Criteria:Patients that fulfilled following criteria were included (1) low energy traumas to the head, (2) pre-injury antithrombotic treatment, (3) > 18 years, (4) reaction level scale (RLS) < 3. Since data collection started at the hospital's radiology registry, we could easily retrieve all patients with low energy traumas to the head who underwent CT scans, were we also included patients without any pre-injury treatment for comparison.Exclusion Criteria:Exclusion criteria were (1) high energy trauma, (2) spontaneous hemorrhage, (3) concealed journals.
Source: ClinicalTrials.gov (NCT05609721). StuddyBuddy aggregates publicly available trial information.