Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting

Conditions: Romberg Disease, Craniofacial Microsomia, Burn Scar, Post-Traumatic Scar (Disorder)

Sex: All

Ages: 18 Years – 50 Years

Phase: PHASE1

Enrollment: 24

Sponsor: University of the Punjab

Summary

The aim of this study is to evaluate the comparison of therapeutic potential of curcumin preconditioned adipose derived stem cells (ASCs) enrichment fat grafting, naïve ASCs enrichment fat grafting and conventional fat grafting to correct facial contour deformities that cause aesthetic complications in patients.

Eligibility Criteria

Inclusion criteriaAge 18-50 years (male or female)Body-mass index 20-30 kg/m²Suitable for liposuction as assessed by the expected cosmetic resultsProvided signed informed consentExclusion criteriaSystemic disorders include autoimmune diseases, hemorrhagic diseases, bone marrow aplasia, sepsis, cancer, and othersLocal disorders include acne, infections and othersRisk factors include smoking, uncompensated diabetes, hypertension, and allergy to the drugs used for general anesthesiaMicrobiological contamination of either the cell culture or the transplanted tissue

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05610878). StuddyBuddy aggregates publicly available trial information.