Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.

This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation mechanism of acupuncture intervention on hot flashes based on integrated PET/MRI technology.

Inclusion Criteria:Aged 30-75 years old;Adjuvant hormone therapy (eg, tamoxifen and/or aromatase inhibitors) with or without ovarian function suppression has been administered for at least 4 weeks and is currently on treatment;Patients with persistent hot flashes for at least 4 weeks and with a frequency of more than 14 hot flashes per week (2 times per day) in the week before inclusion in the study, the weekly average hot flash composite score is 3-4;Patients after surgery and chemotherapy (if any);Eastern Cooperative Oncology Group score of 0-1 points.Sign the informed consent and participate in the clinical observation voluntarily.Exclusion Criteria:Tumor metastases, undergoing chemoradiotherapy or planning surgery;Pharmacological intervention for hot flashes with hot flash treatment drugs such as selective serotonin reuptake inhibitors (SSRIs) and/or anticonvulsants for at least 4 weeks prior to study initiation;Patients receiving phytoestrogens, tibolone or analogs, verapril, or specific homeopathic medicines;Started or changed adjuvant hormone therapy within the past week, or who planned to start or change adjuvant hormone therapy in the past 14 weeks, pregnant or breastfeeding patients;Bleeding or coagulation disorders with obvious uncontrolled infectionPsychiatric illness or family history; neurological disorder or family history; seizure possibility or history of seizures.