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NCT05615116
Clinical Study on the Distribution of Digestive Tract Microbiota Before and After Ileocecal Resection in Crohn's Disease
Conditions: Crohn Disease, Microtia, Ileocecal; Lesion
Sex: All
Enrollment: 60
Sponsor: Shanghai 10th People's Hospital
Location: China
Summary
In this study, the microbiota sequencing was used to investigate the changes of microbiota in the terminal ileum and the middle part of ascending colon, the mesenteric adipose tissue of ileum and ascending mesocolon, and oral cavity of patients with Crohn's disease before and after ileocecal resection, so as to further explore the role of ileocecal region in inducing remission of disease.
Eligibility Criteria
Inclusion Criteria:Clinical diagnosis of Crohn's diseaseExclusion Criteria:Serious oral diseases (e.g.
dental caries, periodontal disease) Other acute or chronic gastrointestinal diseases Probiotics or prebiotic consumption and antibiotic use within 1 month
Source: ClinicalTrials.gov (NCT05615116). StuddyBuddy aggregates publicly available trial information.
