Effect of Body Position on Hemodynamics in Patients With Acute Ischemic Stroke Undergoing Ultra-early Reperfusion Therapy

The aim of this study was to determine the differences in hemodynamics between different positions in patients undergoing ultra-early reperfusion therapy.

Inclusion Criteria:Age≥18 years, < 80 years, regardless of sex；Patients with clinically confirmed acute ischemic stroke who received intravenous thrombolysis or emergency endovascular treatment;Baseline National Institute of Health stroke scale（NIHSS）score ≤25;Baseline Glasgow Coma Scale (GCS) ≥8;Signed and dated informed consent is obtainedExclusion Criteria:The patient has clear indications or contraindications, such as active vomiting, spinal cord injury；Clinicians considered that the assigned body position could not be maintained; Patients unable to cooperate with all noninvasive beat-by-beat continuous BP monitoring;Poor temporal window penetration;Patients with diseases that seriously affect hemodynamics, such as atrial fibrillation, anemia, and hyperthyroidism;Previous history of atrial fibrillation or ECG showing atrial fibrillation or arrhythmia;Pregnant or lactating women;Poor treatment compliance;Complicated with severe systemic diseases, such as heart failure, respiratory failure, renal failure, gastrointestinal bleeding, coagulopathy, malignant tumors.