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Completed
NCT05618574
Nitrite Supplementation in Long COVID Patients
Conditions: Long COVID, Cardiorespiratory Fitness
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 17
Sponsor: VA Office of Research and Development
Location: VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA Pittsburgh Pennsylvania
Summary
Potential benefits of a nitrate-rich juice supplement to improve skeletal muscle function and associated physical capacity will be studied in patients with Long COVID. Consenting patients with Long-COVID will be randomized to receive Beet-It nitrate beverage group versus a nitrate-depleted placebo beverage. Both groups will receive physical therapy at the long COVID Clinic at VAPHS with therapeutic goals to improve strength, balance, inspiratory, and aerobic capabilities. Physical therapy will last for 2 weeks and include 2 or 3 sessions with a physical therapist a week depending on each individual's exercise tolerance. These sessions can take place on-site or at home (or a hybrid combination) All participants will undergo functional assessments and tissue assessments before and after the 14-day study intervention.
Eligibility Criteria
Inclusion Criteria:
* Veterans with prior COVID-19, with residual symptoms of long COVID including increased fatigability.
* Inclusion limited to age 18 and over
Exclusion Criteria:
* Blood pressure \
Source: ClinicalTrials.gov (NCT05618574). StuddyBuddy aggregates publicly available trial information.