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Completed NCT05618574

Nitrite Supplementation in Long COVID Patients

Conditions: Long COVID, Cardiorespiratory Fitness

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 17
Sponsor: VA Office of Research and Development

Location: VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA Pittsburgh Pennsylvania

Summary

Potential benefits of a nitrate-rich juice supplement to improve skeletal muscle function and associated physical capacity will be studied in patients with Long COVID. Consenting patients with Long-COVID will be randomized to receive Beet-It nitrate beverage group versus a nitrate-depleted placebo beverage. Both groups will receive physical therapy at the long COVID Clinic at VAPHS with therapeutic goals to improve strength, balance, inspiratory, and aerobic capabilities. Physical therapy will last for 2 weeks and include 2 or 3 sessions with a physical therapist a week depending on each individual's exercise tolerance. These sessions can take place on-site or at home (or a hybrid combination) All participants will undergo functional assessments and tissue assessments before and after the 14-day study intervention.

Eligibility Criteria

Inclusion Criteria: * Veterans with prior COVID-19, with residual symptoms of long COVID including increased fatigability. * Inclusion limited to age 18 and over Exclusion Criteria: * Blood pressure \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05618574). StuddyBuddy aggregates publicly available trial information.