Effects of Isolated LBBB on Maximal Functional Capacity

Sex: All

Ages: 18 Years – 90 Years

Healthy volunteers: 1

Enrollment: 148

Sponsor: Fundación para la Investigación del Hospital Clínico de Valencia

Summary

Left bundle branch block (LBBB) has been commonly associated with adverse cardiovascular (CV) events, but the effect of an isolated LBBB on maximal functional capacity is not well characterized.The study's main objective is to evaluate the effect of LBBB on maximum functional capacity.

Eligibility Criteria

Inclusion Criteria:Adult >18 years oldECG criteria of left bundle branch block (for controls without left bundle branch block )Provide informed consentExclusion Criteria:Inability to perform a maximal baseline exercise test;Structural heart disease, valve heart disease or diastolic dysfunction estimated by two-dimensional echocardiography;Previous ischemic heart disease, heart failure, myocardiopathy or myocarditisEffort angina during cardiopulmonary exercise testing (CPET);Any moderate pulmonary disease;AnaemiaLeft ventricular ejection fraction < 55%.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05643404). StuddyBuddy aggregates publicly available trial information.