Stroke Volume Variations and Pulse Pressure Variations Under... | Clinical Trial | StuddyBuddy@endsection Stroke Volume Variations and Pulse Pressure Variations Undergoing Artificial Pneumothorax Surgery
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Completed NCT05644405

Stroke Volume Variations and Pulse Pressure Variations Undergoing Artificial Pneumothorax Surgery

Conditions: Artificial; Complications, Heart

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 6
Sponsor: Chinese PLA General Hospital

Location: China

Summary

Stroke volume variation (SVV) and pulse pressure variation (PPV) have been thought to be sensitive predictors of fluid responsiveness in mechanically ventilated participants. In this paper, the investigators reported a special group of people to use SVV and PPV during their operation. The maintenance of hemodynamic stability and the critical organ perfusion is crucial to the treatment for patients with artificial Pneumothorax during esophageal surgery, because artificial pneumothorax causes incomplete ventilation of one lung. In addition, artificial pneumothorax may seriously affect theparticipant's heart and lung function, brings more challenges to the intraoperative anesthetic management, expecially in volume management. Little information is available about the accuracy of SVV and PPV to predict fluid responsiveness in participants with artificial Pneumothorax during esophageal surgery. It is unclear whether it will affect the accuracy of SVV and PPV, and whether it will cause the change of their threshold values. The investigators will discuss it in the passage and the investigators will give an preliminary mechanism to explain the results.

Eligibility Criteria

Inclusion Criteria:Must be arranged for thoracoscopic surgical treatment of esophageal cancer Must be mechanically ventilated with artificial Pneumothorax during the operation Must be normal in Allen test.Exclusion Criteria:Hypertension Coronary heart disease Arrhythmia Left ventricle ejection fractions < 50% (EF<50%) Pulmonary hypertension Congenital cardiovascular malformation Peripheral vascular disease Long-term history of oral vasoactive drugs

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05644405). StuddyBuddy aggregates publicly available trial information.