The Prognostic Value of 18F-PFPN PET Imaging in Patients With Malignant Melanoma

This is a monocentric prospective study. This study aims to investigate the prognostic value of the novel melanin-targeted imaging modality 18F-PFPN PET in patients with melanoma and seek independent prognostic factors for progression-free survival (PFS) and overall survival (OS). The patients with clinically highly suspected or confirmed melanoma who underwent 18F-PFPN and 18F-FDG PET scans will be enrolled consecutively. Patients' PET images, clinical characteristics, and follow-up information will be collected for prognostic analyses. This study plans to set the sample size as 100 cases.

Inclusion Criteria:Patients with histopathologically confirmed melanoma;Patients with complete clinical and follow-up data (including TNM stage, subtypes, and treatment strategies).Exclusion Criteria:Uncertain histopathology;A history of other malignancies.