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Recruiting NCT05646381

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Conditions: Aortic Stenosis

Sex: All
Ages: 50 Years – 80 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 502
Sponsor: Novartis Pharmaceuticals

Location: Heart Center Research Llc Huntsville Alabama

Summary

The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in slowing the progression of calcific aortic valve stenosis.

Eligibility Criteria

Inclusion Criteria: * Male and female ≥50 to \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05646381). StuddyBuddy aggregates publicly available trial information.