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NCT05646381
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Conditions: Aortic Stenosis
Sex: All
Ages: 50 Years – 80 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 502
Sponsor: Novartis Pharmaceuticals
Location: Heart Center Research Llc Huntsville Alabama
Summary
The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in slowing the progression of calcific aortic valve stenosis.
Eligibility Criteria
Inclusion Criteria:
* Male and female ≥50 to \
Source: ClinicalTrials.gov (NCT05646381). StuddyBuddy aggregates publicly available trial information.