CSF Biomarkers in Idiopathic Intracranial Hypertension

Aim of the study is to high lighten the rule of CSF biomarkers in early diagnosis of IIH and in follow up to reach to a definite clinically based decision if this patient will improved on medical treatment or that patient is in need for surgical intervention.

Inclusion Criteria:- 1. All patients with signs and symptoms of increased intracranial pressure (headaches, nausea, vomiting, transient visual obscurations, papilledema).2. CSF opening pressure >25 cm water with normal CSF composition.Exclusion Criteria:1. localizing neurologic signs, except for unilateral or bilateral sixth cranial nerve palsy.2. Evidence of hydrocephalus, mass, infection, structural, or vascular lesion (including venous sinus thrombosis) on imaging.3. Patients with IIH who undergo surgical intervention (thecoperitoneal shunt or optic nerve fenestration) 4. Other identified causes of increased ICP.