Transmural Collaborative Care Model for CVRM and Medication Review for Patients Using Antipsychotics

Currently, monitoring of usage and effects of antipsychotic treatment and cardiovascular risk screening in patients with severe mental illness or antipsychotic treatment is not sufficient.A transmural collaborative care model for cardiovascular risk management and medication review for patients using atypical antipsychotics in general practice (TACTIC) was developed. This trial aims to assess the effectiveness of TACTIC regarding predicted cardiovascular risk and mental quality of life.

Inclusion Criteria:using atypical antipsychotic medication for at least 3 months at baselinethe atypical antipsychotic medication is prescribed by the general practitionera 10-year cardiovascular risk of at least 5% (as measured with QRISK3 score) at baselineExclusion Criteria:diagnosis of dementia or organic psychosisdiagnosis of cardiovascular disease (acute myocardial infarction, acute coronary syndrome, heart failure, ischemic stroke, transient ischemic attack, peripheral artery disease, aortic aneurysm or a revascularization procedure, i.e. percutaneous coronary intervention or coronary artery bypass grafting)