Histological Profiles of Lung Allograft Transbronchial Biops... | Clinical Trial | StuddyBuddy@endsection Histological Profiles of Lung Allograft Transbronchial Biopsies and Clinical Outcomes After Lung Transplantation
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Completed NCT05655208

Histological Profiles of Lung Allograft Transbronchial Biopsies and Clinical Outcomes After Lung Transplantation

Conditions: Lung Transplant Rejection

Sex: All
Ages: 18 Years – N/A
Enrollment: 498
Sponsor: Paris Translational Research Center for Organ Transplantation

Summary

Lung transplantation is the only curative treatment for individuals with end-stage lung disease. Understanding the lung allograft's histological lesions, which is key for the patient management, remains difficult because of the multiplicity of lesions associated with graft outcome and their interpenetration.The goal of this observational study is to identify clusters of histological lesion on transbronchial biopsies in Lung transplant recipient prospective cohort.The main question[s] it aims to answer are:what are the different pattern of histological lesion?what are the graft outcome associated with the different clusters?

Eligibility Criteria

Inclusion Criteria:i) age greater than 18 years,ii) single or bilateral lung transplantation,iii) having at least one transbronchial biopsy available for analysisiv) consent their clinical data to be used for researchExclusion Criteria:• Biopsies with at least one missing value in the standardized clinical report were excluded

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05655208). StuddyBuddy aggregates publicly available trial information.