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Enrolling By Invitation
NCT05666492
"Platelet Rich Plasma for the Management of Post-Viral Olfactory Dysfunction.
Conditions: Olfactory Disorder, Olfaction Disorders
Sex: All
Ages: 18 Years – N/A
Phase: NA
Enrollment: 120
Sponsor: Thomas Jefferson University
Location: United States
Summary
SARS COV-19 has resulted in prolonged olfactory dysfunction in many patients.
The investigators aim to compare the effect of topical platelet-rich plasma (test) vs saline (placebo) in patients with covid-related post-viral olfactory dysfunction.
Eligibility Criteria
Inclusion Criteria:Adult patients suffering from either post-viral or post-COVID smell loss of any duration, without a history of nasal surgery, nasal polyposis, chronic rhinosinusitis, or intranasal tumorsPatients who are post-COVID must report at least a positive home test on historyPatients with post-viral etiology must have recall of a viral illness that immediately preceded smell lossExclusion Criteria:History of olfactory dysfunction predating COVID-19 infectionHistory of trauma, previous surgery, or obstructive cause of OD (nasal polyps, chronic rhinosinusitis)PregnancyPatients who are unable to provide consentPatients with known bleeding disordersPatients with known malignancies
Source: ClinicalTrials.gov (NCT05666492). StuddyBuddy aggregates publicly available trial information.
