Effect of Probiotics Among Overweight and Obese Saudi Adults

Obesity is classified as a low-grade chronic and systemic inflammatory disease and results from complicated interactions between genes and environmental factors, which leads to many diseases and affects the quality of life. There are growing interests in the effectiveness of probiotics as a supplementation to treat obesity through regulating microbiota host metabolism. Probiotics may influence the interplays among gut, brain, adipose, and liver in a way leading to weight. Since limited studies have been conducted on human subjects, more investigation is needed in this field. Therefore, this study sheds light on the investigation of the anti-obesity effect of probiotic supplementation.

Inclusion Criteria:Adult's male and female ages between 19 to 40 years.BMI (in kg/m2) from 25 to 35, (WHO, n. d.) Waist Circumference (WC) > 88 cm (women) or > 102 cm (men) (lean et al, 1995).Stable body weight in the previous month of the trial.Exclusion Criteria:Participants who suffer from diseases and on treatment, such as immune system diseases or thyroid disorders.Pregnant women or who plans to be pregnant.Participants who had gastrointestinal surgery.Hormone replacement therapy.Participants who taking antibiotic.Participants who consume probiotic or prebiotic supplementation regularly.