Urine VOC Investigation in Bladder Cancer Diagnosis

The goal of this study to investigate the volatile organic compounds (VOCs) in the urine samples of both healthy individual and bladder cancer patients, using gas chromatography - mass spectrometry. Researchers aim to find a set of certain VOCs specific to bladder cancer and use this set to construct a diagnostic model that can help diagnosing bladder cancer. Participants will be asked to collect their early morning midstream urine in a predesignated container. Researchers will compare urine VOCs from bladder cancer patients and healthy individuals to see if there is any VOC whose concentration differ significantly among the two groups.

Inclusion Criteria:bladder tumor confirmed by cystoscopy and radiologywomen of childbearing age with negative urine pregnancy test resultwilling to participate in this trial and sign the informed consent formExclusion Criteria:patient with 1) uncontrollable urinary tract infection; 2) severe systemic disease; 3) history of malignancy within the past 5 years; 4) pregnancy or lactationpatient involved in other clinical trialsother situations researcher considered to be ineligible for this trial