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NCT05675878
Confirmation of Diet as a Treatment for Gulf War Illness
Conditions: Gulf War Syndrome, Gulf War Illness
Sex: All
Ages: 50 Years – 75 Years
Phase: PHASE3
Enrollment: 160
Sponsor: American University
Summary
This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention.
The main objectives of this study are: 1) to confirm previous findings of treatment response to the diet in a larger and more diverse group; 2) to examine how changes in the nervous system may be the reason for improvement; and 3) to identify markers which change in the blood after one month on the diet.
Participants will have baseline measures collected and then will be randomized into the intervention or wait-listed control group, which they will follow for one month before being reassessed.
Eligibility Criteria
Inclusion Criteria:Males and Females of all races and ethnicities who are ≤75 yrs of ageServed in the 1990-1991 Persian Gulf WarFulfill both Center for Disease Control (CDC) and Kansas definitions of Gulf War IllnessStable medication regimen for ≥1 month and willing to keep medications and supplements stable throughout study participationExclusion Criteria:Recent substance use disorder (past year)Unwilling to stop using alcohol, tobacco (including vaping) and/or marijuana; or unwilling to change dietDiagnosed seizure disorder or severe asthma requiring past hospitalizationCurrently taking medication which affects glutamatergic or GABAergic neurotransmission (but can work with their physician to wean off of these medications prior to participating)
Source: ClinicalTrials.gov (NCT05675878). StuddyBuddy aggregates publicly available trial information.