Do Patients With Fish or Shellfish Allergy Tolerate the Consumption of Fish Oil Supplements? A Clinical Study

The purpose of this clinical study is to test whether patients with fish or shellfish allergy can ingest different types of fish oil supplements without having an allergic reaction.To achieve this, the recruited participants will be asked to:provide a blood sample (used for Basophil Histamine Release Assay)undergo a skin-prick-testpartake in multiple oral provocationsThese three tests will indicate the likelihood that the participants can consume fish oil supplements without adverse allergic reactions (See the detailed description for an explanation of the tests).The investigators will test the participants tolerance for three different types fish oil supplements: Fish oil, Cod liver oil, and krill oil.

Inclusion Criteria:Adult (≥18 years old)Legally competentUnderstands DanishExclusion Criteria:Current use of antihistamine, immunosuppressants, and/or anti-IgE-treatment that cannot be safely terminated during the study periodThe presence of severe diseases such as: Cardiovascular disease, asthma, cancer, liver disease, kidney disease, hematological diseases, neurological diseases, dementia, immunological diseases, and endocrine diseasesChronic urticariaSevere atopic eczemaPregnancy and/or breastfeedingParticipation in another clinical study the previous three monthsKnown excessive use of alcohol and/or substance abuse