Comparing Platelet-Rich Plasma (PRP) Centrifugation Methods on Thrombocyte Concentration and Clinical Improvement of Androgenetic Alopecia

This research is a preliminary, randomized, double blind clinical trial, which will examine the differences in PRP preparation methods, a single-spin centrifugation of 3000 rpm in 15 minutes compared to a double-spin centrifugation of 1500 rpm in 6 minutes followed by 2500 rpm in 15 minutes, on the results of Thrombocyte Concentration and Clinical Improvement of Androgenetic Alopecia.

Inclusion Criteria:Met the criteria of androgenic alopecia (Hamilton Norwood grade III-IV)Men between ages 25-59 years oldHave stopped taking topical anti-androgen or minoxidil for at least one month, or oral anti-androgen or minoxidil for at least three monthsExclusion Criteria:alopecia of any other typesubject with a history of keloid or blood coagulation disorders underwent anticoagulant therapysubjects on Non-Steroidal Anti-Inflammatory Drugs (NSAID) medications in seven days prior to the studysubjects who had hair treatment using growth factors, including PRP and microneedling within at least six months prior to the study.