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NCT05683184
OMAR Opioid Use Disorder
Conditions: Healthy Control, Opioid Use Disorder
Sex: All
Ages: 18 Years – 55 Years
Healthy volunteers: 1
Enrollment: 30
Sponsor: Yale University
Summary
The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.
Eligibility Criteria
Inclusion Criteria:Able to provide informed consentMale and female 18-55 years old (inclusive)DSM-5 diagnosis of opioid use disorder (for OUD group)Physically healthy i.e., no clinically unstable medical conditionsWritten informed consent and have capacity to consent and comply with study proceduresExclusion Criteria:Current neuro-psychiatric illness or severe systemic disease (opioid use disorder is permitted in the OUD group).Presence of ferromagnetic metal in the body or heart pacemakerHave had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limitsAre claustrophobic
Source: ClinicalTrials.gov (NCT05683184). StuddyBuddy aggregates publicly available trial information.
