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NCT05686096
A Study to Evaluate the Absorption, Metabolism, and Excretion (ADME) of BMS-986435
Conditions: Healthy Volunteers
Sex: Male
Ages: 18 Years – 55 Years
Healthy volunteers: 1
Phase: PHASE1
Enrollment: 8
Sponsor: Bristol-Myers Squibb
Summary
The purpose of this study is to determine the absorption, metabolism, excretion; and to evaluate the safety and tolerability of BMS-986435 in healthy male participantsParticipants will be admitted to the study site for 3 weeks.
Eligibility Criteria
Key Inclusion Criteria:Body mass index between 18 and 32 kg/m^2, inclusive, at screening.
- Healthy male participants as determined by the investigator and sponsor.Adequate acoustic windows to enable accurate transthoracic echocardiogram (TTE) assessment of parameters of left ventricular (LV) systolic function by TTE.Documented left ventricular ejection fraction (LVEF) ≥ 60% at screening.Key Exclusion Criteria:Any acute or chronic medical illness.History of dizziness and/or recurrent headaches (ie, daily headaches lasting for a 1-week duration in the last month prior to study intervention administration).Head injury in the last 2 years, intracranial tumor, or aneurysm.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.
Source: ClinicalTrials.gov (NCT05686096). StuddyBuddy aggregates publicly available trial information.
