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Active Not Recruiting
NCT05687344
Intensive Postpartum Antihypertensive Treatment
Conditions: Hypertensive Disorder of Pregnancy
Sex: Female
Ages: 18 Years – 45 Years
Healthy volunteers: Yes
Phase: PHASE3
Enrollment: 60
Sponsor: Medical College of Wisconsin
Location: Froedtert Hospital Milwaukee Wisconsin
Summary
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.
Eligibility Criteria
Inclusion Criteria:
* HDP diagnosis (gestational hypertension or preeclampsia) according to ACOG guidelines
* Postpartum day 0-3 and prior to discharge
* Able to communicate in English or in Spanish
* Age 18 - 45
Exclusion Criteria:
* Pre-gestational hypertension
* Pre-gestational diabetes ( type 1 or type 2)
* Intent to transfer postpartum to an outside institution of the participating centers
* Known allergy to nifedipine or other significant contraindication to nifedipine
* Inability or unwillingness to provide informed consent
Source: ClinicalTrials.gov (NCT05687344). StuddyBuddy aggregates publicly available trial information.