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Recruiting NCT05691387

Comparison of Active Cycle of Breathing Technique and Pursed Lip Breathing With TheraPep

Conditions: Chronic Obstructive Pulmonary Disease Exacerbation

Sex: All
Ages: 35 Years – 65 Years
Phase: NA
Enrollment: 40
Sponsor: University of Jazan

Location: Saudi Arabia

Summary

The purpose of this study is to investigate the short-term effects of two different breathing techniques (the active cycle breathing technique (ACBT) and the pursed lip breathing technique (PLB)) with Thera PEP® on the clearance of secretions and the oxygen saturation of individuals who have recently experienced an acute exacerbation of chronic obstructive pulmonary disease (COPD) in individuals who have recently experienced an acute exacerbation of COPD (COPD). Thirty patients will each have an acute COPD exacerbation seen on them, and then they will be randomly allocated to one of two groups (1. ACBT and PLB; 2. Thera PEP). Participants in a study employing a design known as a within-subject randomized crossover will be given the instruction to carry out each procedure on consecutive days as part of the study. In this study, the dependent variables will include blood pressure, heart rate, oxygen saturation (SpO2), respiratory rate, peak expiratory flow rate (PEFR), visual analog scale (VAS), sputum volume, and the breathlessness, cough, and sputum scale. In addition, the independent variables will include sputum volume (BCSC). The patient's desired course of treatment will also be taken into account. These dependent variables will be examined at three distinct moments in time: at the beginning of the study (the baseline), immediately after treatment, and thirty minutes after treatment has been completed.

Eligibility Criteria

Inclusion Criteria:Hospitalization will be required for these people because of a rapid worsening of their chronic obstructive pulmonary disease. An upper respiratory tract infection, a high temperature for no apparent reason, an increase in wheezing and coughing, or a rise in respiratory rate or heart rate above baseline will all be considered to be indications suggesting an acute exacerbation of COPD.Exclusion Criteria:Co-morbidities (including but not limited to angina, indication for ventillatory support, neurological deficits, severe hemodynamic instability (including but not limited to cor pulmonale, cardiac arrhythmias, pulmonary embolism, pneumothorax, congestive heart failure, and GOLD stage IV: very severe COPD), and indication for ventillatory support will be considered for exclusion of these individuals from the study.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05691387). StuddyBuddy aggregates publicly available trial information.