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Recruiting
NCT05696808
Effect of Indian Hepatoprotective Diet in Reversibility of NAFLD
Conditions: Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
Sex: All
Ages: 18 Years – 60 Years
Phase: NA
Enrollment: 60
Sponsor: Institute of Liver and Biliary Sciences, India
Location: India
Summary
The modality of lifestyle modification including low calorie diets along with normal protein and moderate physical activity is the safest standard medical treatment for NAFLD in general.
There are many benefits of weight loss to the patients with NAFLD.
Besides the improvement in the features of metabolic syndrome, weight loss with IHPD would certainly improve the overall vitality and well being of the patients.
The results of study will help to delineate a protocolized care for the management of NAFLD with metabolic syndrome thus helping other patients also in the future.
Eligibility Criteria
Inclusion Criteria:Patients recently diagnosed (<3 months)diagnosed on the basis of ultrasound and /or liver transient eleastography (controlled attenuation parameter; CAP >250)Having components of metabolic syndrome like Hyperglycemia, central obesity, hypertension, hypertriglyceridemia, and low HDL cholesterol levels).Exclusion Criteria:Pregnant & lactating womenAge <18 and >55 yearsIndividuals who had been hospitalised with complications of Diabetes mellitus, Chronic Kidney disease, Hypertension in the previous 6 monthsThose with intake of antibiotics within last monthSeriously ill and bed ridden patientsPatients with viral hepatitisPatients with significant alcohol consumption (regular consumption of > 10g per day for females and > 20g/d in males),Patients having chronic inflammatory bowel disease or any chronic and autoimmune diseases will be excludedPatients with NAFLD with associated hypertriglyceridemia requiring administration of statins.
Source: ClinicalTrials.gov (NCT05696808). StuddyBuddy aggregates publicly available trial information.