Safety and Efficacy of Evolocumab in Ischemic Stroke

Sex: All

Ages: 18 Years – N/A

Phase: PHASE4

Enrollment: 200

Sponsor: Second Affiliated Hospital of Guangxi Medical University

Summary

The goal of this clinical trial is to evaluate the effect of evolocumab in combination with statin therapy (atorvastatin) in acute ischemic stroke (AIS).

Eligibility Criteria

Inclusion Criteria:Patient age between 18-80 yearsTime of onset: within 1 weekNIHSS score ≤12Acute ischemic stroke confirmed by head CT or MRIPremorbid mRS ≤1Signed informed consentExclusion Criteria:Intracranial hemorrhage found by head CTSevere hepatic or renal dysfunctionPregnant femalesAbnormal elevation of creatine phosphokinaseBlood sugar is out of controlReceiving statins within 1 month before onsetNot willing and able to comply with scheduled visits, lifestyle guidelines, treatment plan, laboratory tests, and other study proceduresUnsuitable for this clinical studies assessed by researcher

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05697185). StuddyBuddy aggregates publicly available trial information.