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Not Yet Recruiting NCT05698589

COMpassion for Psychiatric Disorders And Self-Stigma

Conditions: Bipolar Disorder, Schizophrenia, Depression, Borderline Personality Disorder, Autism Spectrum Disorder

Sex: All
Ages: 18 Years – N/A
Phase: NA
Enrollment: 336
Sponsor: University Hospital, Strasbourg, France

Summary

People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into society . Stigmatization can also be assimilated by patients themselves - i.e. self-stigma. Self-stigma is involved in diminished coping skills that lead to social avoidance and difficulties in adhering to care . Reducing self-stigma and its emotional corollary, shame, is thus crucial to attenuate the disability associated with mental illness. Shame is inherent to self-stigma and leads to difficulties in adhering to care as well as greater severity of clinical presentations . Compassion Focused Therapy (CFT) is a third wave cognitive behavioral therapy that targets shame reduction and hostile self-to-self relationship and allows for symptom improvement while increasing self-compassion, a major resilience factor . Although shame is a prominent part of the concept of self-stigma, the efficacy of CFT has never been evaluated in individuals with high levels of self-stigma.In this study, the investigators will evaluate the efficacy and acceptability of a group based CFT program on decreasing self-stigma, compared to treatment as usual (TAU) and a psychoeducation program whose efficacy has been assessed in a previous trial.

Eligibility Criteria

Inclusion Criteria:Patient ≥18 years of agePatient informed of the results of the preliminary medical examinationPatient affiliated to a social health insurance plan (beneficiary or beneficiary's family)Patient with one or several diagnoses of chronic psychiatric disorder (schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major depression, borderline personality disorder) or a neurodevelopmental disorder (autism spectrum disorder) treated as an outpatient or in a day hospitalCGI-Severity score<6 assessed by the psychiatrist (Berk et al., 2008) ISMI score indicating moderate to high self-stigma (>2.5; Lysaker et al., 2007)Exclusion criteria:Patient in an exclusion period determined by a previous or ongoing studyPatient participating in an interventional study involving psychotherapy or an experimental drugPatient in acute episode of their disorder according to the CGI Severity scorePatient in a medical emergency or immediate life-threatening situationPatients with an intellectual disability (IQ<70) estimated via the fNART (Mackinnon & Mulligan, 2005)12. Legal issues: care under constraint or patient deprived of freedom because of a judicial measure 13. Patient who does not speak and read French sufficiently

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Source: ClinicalTrials.gov (NCT05698589). StuddyBuddy aggregates publicly available trial information.