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Completed
NCT05699720
Acute Exacerbation of COPD and Nebulized Magnesium Sulphate
Conditions: Chronic Obstructive Pulmonary Disease Exacerbation, Magnesium Sulfate
Sex: All
Ages: 30 Years – 70 Years
Phase: NA
Enrollment: 160
Sponsor: King Edward Medical University
Location: Pakistan
Summary
This study is designed to determine the effect of Nebulized Magnesium Sulphate as an add-on therapy with conventional treatment on In-hospital outcome in patients having acute exacerbation of COPD.
Eligibility Criteria
Inclusion Criteria:1.
The age of patient should between 30 to 70 years.
2. The patient could be male or female.
3. The duration of COPD must be less than 10 years.
4. Acute exacerbation of COPD requiring hospital admission and any two out of four criteria: I. Increase in the purulence or quantity of sputum II.
Dyspnea grade 3, 4 or 5 according to MRC scale (Annexure attached) III.
PEFR <200 L/min IV.
Respiratory acidosis on arterial blood gas analysisExclusion Criteria:- 1. Known case of other pulmonary parenchymal disease diagnosed by history, examination and previous medical records.2. Bronchogenic carcinoma diagnosed by history and previous records.
3. Pulmonary edema diagnosed based on history, examination and investigations.
Source: ClinicalTrials.gov (NCT05699720). StuddyBuddy aggregates publicly available trial information.
