The Diabetes Prevention Program Outcomes Study AD/ADRD... | Clinical Trial | StuddyBuddy@endsection
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Enrolling By Invitation
NCT05704309
The Diabetes Prevention Program Outcomes Study AD/ADRD Project
Conditions: Diabetes, Alzheimer Disease, Dementia, Vascular, Dementia, PreDiabetes
Sex: All
Healthy volunteers: 1
Enrollment: 1976
Sponsor: Marinella Temprosa
Location: United States
Summary
The DPPOS AD/ADRD project will address the overarching question: What are the determinants and the nature of cognitive impairment among persons with pre-diabetes (PreD) and type 2 diabetes (T2D), who are a high-risk group for cognitive impairment and represent a large fraction of the United States (US) population?
This U19 proposal addresses the National Alzheimer's Project Act goal to "prevent, halt, or reverse AD" in the high-risk group of persons with pre-diabetes and type 2 diabetes, who represent over half of the population aged 60 years and older in the US.
Eligibility Criteria
Inclusion Criteria:All surviving participants originally randomized in the Diabetes Prevention ProgramFor Brain Imaging subcohort, only participants aged 55 years and older and those without contraindication to MRI will be included.
Contraindications to MRI include the inability to lie flat, claustrophobia, and the presence of indwelling metallic objects, medical or non-medical, that are not 3T MRI compatible.Exclusion Criteria:-
Source: ClinicalTrials.gov (NCT05704309). StuddyBuddy aggregates publicly available trial information.