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Completed NCT05709873

Narcolepsy Nightmare Study

Conditions: Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Type 2, Narcolepsy Without Cataplexy

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 7
Sponsor: Northwestern University

Location: Northwestern University Chicago Illinois

Summary

The goal of this clinical trial is to test two behavioral treatments for nightmares in adults with narcolepsy. The main questions it aims to answer are: * Is imagery rehearsal therapy (IRT) effective for narcolepsy-related nightmares? * Does adding targeted dream control (TDC) to IRT make it more effective? Participants will be randomized to one of two treatment groups and will be asked to: * Complete a daily log of sleep symptoms for up to 13 weeks. * Attend 7 sessions of treatment. * Complete questionnaires before and after treatment. * Go to the research lab in Evanston, IL to complete a sleep study during a daytime nap (Chicago area residents only).

Eligibility Criteria

Inclusion Criteria (all participants): * Diagnosis of narcolepsy * Age 18 or older * Speak English * Live in the United States * Receiving standard medical care for narcolepsy * Sleep and psychiatric medications stable for at least 3 months * Nightmare frequency of ≥3 times per week * Nightmare Disorder Index score indicates probable nightmare disorder Inclusion Criteria (Chicago area participants): * Able to attend a study appointment in Evanston, IL * Able and willing to not take wake-promoting medications on day of lab visit Exclusion Criteria: * History of a neurological disorder that might alter EEG * Currently engaged in sleep- or trauma-focused psychotherapy * Previous behavioral treatment for nightmares * Medical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatment * Untreated sleep apnea (AHI ≥ 5)

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05709873). StuddyBuddy aggregates publicly available trial information.