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Completed
NCT05712837
Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild to Moderate Acne Vulgaris
Conditions: Acne Vulgaris
Sex: All
Ages: 13 Years – 22 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 60
Sponsor: Combined Military Hospital Abbottabad
Location: Pakistan
Summary
To compare the efficacy of 25% trichloroacetic acid peel versus 30% salicylic acid peel in mild to moderate acne vulgaris.Study Design: Randomized Control Trial.
Place And Duration of Study: Department of Dermatology, CMH Abbottabad from 01 Jun 2022 to 30th Nov, 2022.Methodology: A total of 60 patients presented with mild or moderate acne vulgaris were randomized into two groups comprising 30 patients in each group and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks.
Patients in Group A were treated with 25% TCA peel whereas patients in Group B were treated with 30% SA peel.
At the end of therapy after 12 weeks, evaluation of active acne was done by individual lesion counts (comedones, papules and pustules) and calculation of the Michaelsson acne score (MAS).
Eligibility Criteria
Inclusion Criteria:Patients with mild or moderate facial acne vulgaris presented in dermatology opdExclusion Criteria:Patients with grade III or IV acne vulgarispatients taking any acne medications or had taken oral or topical medications in the past 4 weekspregnant female patients or nursing a babypatients with known hypersensitivity to the formulations used in the study or a history of photosensitivityhypertrophic scars, keloidal tendency, active or recurrent herpes simplex infectionactive dermatosisunrealistic expectations
Source: ClinicalTrials.gov (NCT05712837). StuddyBuddy aggregates publicly available trial information.
