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NCT05714618
MR Evidence of Cardiac Inflammation Post-Stroke
Conditions: Stroke, Ischemic, Inflammation, Myocardial Injury
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 44
Sponsor: Luciano A. Sposato
Location: Heart & Brain Lab, Western University London Ontario
Summary
The present study is an investigator initiated, single-centre, prospective, proof-of-concept cohort study aiming to enroll 44 patients with acute middle cerebral artery (MCA) ischemic stroke, involving the right (n=22) and left (n=22) MCA territories and 24 control patients with acute focal neurological symptoms but no evidence of acute brain infarct on DWI-MRI.
Eligibility Criteria
Inclusion Criteria:
• Acute ischemic stroke in the right or left MCA territory. Acute ischemic stroke is defined as acute onset focal symptoms matching an acute brain infarct documented on Head computed tomography or diffusion-weighted imaging (DWI) MRI of the brain showing restricted diffusion.
Exclusion Criteria:
* History of known atrial fibrillation, prior myocardial infarction, coronary artery disease, heart failure, prior cardiovascular surgery or percutaneous intervention.
* Previous stroke (occurred within 3 months before the index event)
* Impaired renal function defined as a creatinine clearance \
Source: ClinicalTrials.gov (NCT05714618). StuddyBuddy aggregates publicly available trial information.
