Changes in Lung Aeration and Inspiratory Effort With and Without Awake Prone

Conditions: Respiratory Distress Syndrome, Ventilation Therapy; Complications

Sex: All

Ages: 18 Years – 90 Years

Phase: NA

Enrollment: 34

Sponsor: Shanghai Zhongshan Hospital

Summary

The investigators aimed to investigate the ventilation homogeneity and transpulmonary pressure during treatments of High-flow nasal cannula(HFNC) and (CPAP) on supine and prone position for non-COVID-19 patients with acute hypoxemic respiratory failure (AHRF).

Eligibility Criteria

Inclusion Criteria:adult patients (18-90 years) who have acute hypoxemic respiratory failure, requiring FIO2 > 0.4 to maintain SpO2 at 90-95% during HFNC at 50 L/minExclusion Criteria:patients who need immediate intubation; refuse to participate in the study; unable to communicate; have contraindication to place the esophageal catheter; unable to use EIT, such as open-chest surgery with chest tube placement; have contraindication for prone positioning, including pregnant, post-abdomen surgery within a week; hypercapnic respiratory failure.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05719103). StuddyBuddy aggregates publicly available trial information.