Osteocrin and Vascular Complications

In this study, we aimed to describe the role of bone-derived factor (osteocrin) in glucose metabolism, micro and macrovascular complications in diabetic patients. Thus, further investigations of the endocrine system through bone-derived hormones may provide as new perspectives on the prediction, prevention, and treatment of diabetes mellitus.

Inclusion Criteria:- Cases of the study will select randomly, based on inclusion criteria that includedPatients were diagnosed with diabetes mellitus according to American Diabetes AssociationAge range 20-70 yearsNo apparent vascular abnormalities and Acute complicationsExclusion Criteria:Patients are excluded for participation in the study ifPatients had past history of cardiovascular events (heart failure or history of coronary artery disease),infections,aacute diabetic complications,diabetic patients on regular hemodialysis .acute illness, malignancy, or pregnancy.