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Recruiting NCT05722067

Improvement of Fertilization Rate and Embryo Quality by Treating Calcium Ionophore in IVF Patients: a Sibling Oocyte Control Study

Conditions: IVF, Infertility, Artificial Oocyte Activation

Sex: Female
Ages: 20 Years – 50 Years
Phase: NA
Enrollment: 200
Sponsor: Chang Gung Memorial Hospital

Location: Taiwan

Summary

GM508 CultActive is a bicarbonate buffered reagent and ready-to-use designed to investigate oocytes of patients with failed fertilization after previous Intracytoplasmatic Sperm Injection cycles. The investigators hypothesize that GM508 CultActive will improve the fertilization rate and embryo development of such IVF patients (a history of poor fertilization, a history of poor embryo quality, and over 40 years old expected challenging to conceive).

Eligibility Criteria

Inclusion Criteria:Low fertilization rate in previous IVF cycle (<30%), orPoor embryo developmental problems in previous IVF cycle, orDiminished ovarian reserve (AMH<1.2 or AFC<5) and/or more than 40 y/o.Exclusion Criteria:Without or just one oocyte picked up

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05722067). StuddyBuddy aggregates publicly available trial information.