Effect of Cryotherapy on Post-endodontic Pain

The goal of this clinical trial is to compare Cryotherapy with occlusal reduction in the reduction of post-endodontic pain in molars with symptomatic apical periodontitis. The main question it aims to answer is:Is there is a difference in post-endodontic pain intensity following cryotherapy or occlusal reduction in patients with symptomatic apical periodontitis on mandibular first molars?Participants will undergo root canal treatment including cryotherapy or post-operative occlusal reduction.Researchers will compare [Cryotherapy, occlusal reduction, and no intervention] to see the intensity of post-endodontic pain.

Inclusion Criteria:Age: 18-70 yearsA patient diagnosed with symptomatic irreversible pulpitis/acute apical periodontitisrequire endodontic therapyMandibular first molars that are diagnosed with symptomatic irreversible pulpitis/acute apical periodontitisHealthy patients without systemic diseasePermanent mature first mandibular molarsExclusion Criteria:Medically compromised patientsPregnant patientsTeeth with incomplete apex formationTeeth with calcified canalsPeriapical abscessPatients on antibiotic therapy