Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Conditions: Mitral Valve Disease

Sex: All

Ages: 18 Years – N/A

Enrollment: 145

Sponsor: Michele De Bonis

Location: Italy

Summary

Degenerative mitral regurgitation (MR) due to prolapse of the posterior leaflet is the most common dysfunction of the mitral valve (MV) in the Western world and is nowadays treated with a variety of surgical techniques. Quadrangular resection combined with annular plication and annuloplasty, as originally described by Carpentier, has been the standard approach for many years, before sliding/folding plasty and artificial chordae gained larger popularity.However, very few studies have been published on thevery long-term results (up to 20 years) of quadrangular resection and annular plication, often reporting only freedom from reoperation rather than from recurrent MR. This study aims to evaluate the very long-term (20 years) clinical and echocardiographic results of this approach, which was used for many years at the beginning of our mitral repair program.

Eligibility Criteria

Inclusion Criteria:Adult patientsAffected by mitral valve posterior leaflet prolapse/flail causing severe mitral regurgitationTreated with quadrangular resection of the posterior leaflet and annulus plicationExclusion Criteria:Other patients

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05724537). StuddyBuddy aggregates publicly available trial information.