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Completed
NCT05725850
The Effect of an Experimental Gel Based on Acmella Oleracea Extract in Reducing Post-bleaching Tooth Sensitivity
Conditions: Tooth Bleaching, Pain, Dentin Desensitizing Agents
Sex: All
Ages: 18 Years – 40 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 50
Sponsor: Universidade Federal do Para
Location: Brazil
Summary
This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing 10% jambu extract (Acmella Oleracea) in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide.
The volunteers of this study were randomized into two different groups - GE (A.
Oleracea extract at 10%) and GP (placebo).
The dental elements of the GE received application of the experimental desensitizing gel on the buccal surfaces of the central incisors, lateral incisors, canines and upper and lower premolars, with a rubber cup in an active way, for 10 minutes.
The GP group also received the application of a placebo gel (without active ingredient), under the same conditions described for the experimental gel.
Subsequently, all groups underwent in-office bleaching treatment with 35% hydrogen peroxide.Post-bleaching sensitivity was collected through a form composed of the visual analogue scale (VAS).
Color measurement was performed at two times: baseline (Ti) and one week after the 3rd bleaching session (Tf).
Eligibility Criteria
Inclusion Criteria:good oral hygieneabsence of active caries lesionsnever having undergone previous whitening therapynot present dental hypersensitivitydon't be a smokernot be pregnantpresent at least 28 teeth in the oral cavity.Exclusion Criteria:volunteers who were under orthodontic treatment,presence of periodontal diseasedental cracks or fracturesrestorations and prostheses on anterior teethextensive molar restorationsgastroesophageal disorderssevere internal dental darkeningpresence of dentinal exposure in anterior and / or posterior teeth.
Source: ClinicalTrials.gov (NCT05725850). StuddyBuddy aggregates publicly available trial information.
