Pain Informed Movement for People With Knee Osteoarthritis

The goal of this clinical trial is to compare a pain informed movement program to standard neuromuscular exercise in people with knee osteoarthritis. The main question it aims to answer are: 1. Are the two interventions a) pain informed movement program plus pain neuroscience education and b) neuromuscular exercise plus standard osteoarthritis education feasible in terms of recruitment, treatment adherence, timelines, data collection procedures, patient follow-up, and resources required? 2. Is there a difference in patient's satisfaction and acceptability of the two programs? 3. Are there any differences in the potential effects of the two programs on subjective pain measures, self-reported function, quality of life, functional leg strength, nervous system pain modulation, brain derived neurotrophic factor and nerve growth factor levels, and psychological factors?

Inclusion Criteria: * \- ≥40 years of age with diagnosis of knee osteoarthritis (OA) by a physician OR; * ≥45 years of age and having activity-related knee joint pain with or without morning stiffness lasting 30 minutes (NICE criteria) * Having an average pain intensity of 3/10 on a numeric pain scale on most days of the past month Exclusion Criteria: * Cannot communicate in English; * Has inflammatory arthritis or other systemic conditions; * Have had lower limb trauma or surgery within the past 6 months; * Have participated in a knee OA exercise program in the prior 3 months; * Have had any injection in the index knee within 3-months prior to baseline assessment * Does not have regular access to the internet * Inability to get up and down from the floor independently * Use of mobility aids * Currently participating in any other drug/device/exercise clinical trial related to OA * Planned absences (e.g., trips away) of \>1 week * Currently receiving other forms of care for knee OA pain (e.g., from a physiotherapist, chiropractor, athletic therapist, kinesiologist) * Does not meet screening for safe participation in exercise according to the Get Active questionnaire from the Canadian Society for Exercise Physiology