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NCT05731531
EGG Test as a Predictor for an Individual Response to Treatment by Various Bariatric Procedures
Conditions: Bariatric Surgery, Gastric Motor Dysfunction, Gastroparesis
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 250
Sponsor: Asian Institute of Gastroenterology, India
Location: India
Summary
Total body weight loss (TBWL) after bariatric endoscopy (BE) is variable.
Gastric emptying may be normal, rapid or delayed in patients with obesity and be a factor in variable BE outcomes.
Gastric myoelectrical activity (GMA) reflects gastric pacemaker activity which controls gastric contractions.
The non-invasive electrogastrogram(EGG) uses standard electrodes positioned on the abdominal surface to record GMA.
The investigators postulate that GMA patterns recorded with EGG will reflect subgroups in regards to stomach electrical physiology in obesity and that these subgroups will be useful in selecting patients for various BE procedures to maximize success of the procedures.
Eligibility Criteria
Inclusion Criteria:Men and women, aged between 18-65 yrsIMC basal ≥ 30 kg/m2Patient undergoing bariatric intervention willing to participate in the studyInformed consent (oral and written) for the tests to be carried out.Exclusion Criteria:Presence of severe cardiac, renal, hepatic, or neurological diseaseLong term use of medication that alter gastric motility (> 4 weeks)Significant alcohol or opioids or narcotics or tobaccoActive malignancy 5.Pregnancy
Source: ClinicalTrials.gov (NCT05731531). StuddyBuddy aggregates publicly available trial information.