Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal

• The evolution of conservative dentistry that adopts the preservation of tooth structure and affected dentin that can remineralize and save the pulp from exposure, in addition to pain and fear that companies' traditional caries removal methods had led to the development of chemomechanical caries removal materials (CMCR).The old generations of CMCR agents were NaOcl-based materials which have disadvantages such as odor taste, Unpleasant smell, high cost, Limited shelf life, and time consumption.• All of the reasons described led to a new generation of CMCR materials depending on Enzymes such as Papain.Brix3000 and Papacarie duo are Papain-based materials with promising effects in caries removal and fewer disadvantages.Selecti-solve is a dental gel whose active ingredient is papain enzyme, it removes dental caries without the need for anesthesia and is selective for the infected dentin layer only which avoids the unnecessary loss of dentin, enamel breaking, and pulp exposure.This study aims to evaluate the efficacy of Papain-based materials compared to old NAOcl-Based materials in reducing the disadvantages of CMCR agents.

Inclusion Criteria:Wide carious lesion (Class 1 Black) on Molars at the middle third of dentine confirmed with a periapical x-rayNo pulp involvement is assured with a periapical radiograph.Good oral hygieneCooperated patient.No oral diseases.Exclusion Criteria:Pulp exposure or bleeding during excavation.PregnancySystematic diseasesGingival and periodontal involvement.Lack of patient cooperation.