A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions

Peripheral pulmonary lesions are of growing importance in respiratory field. Early detection of lung cancer, tuberculosis and other diseases often needs a bronchoscopic investigation with different types of navigation. Current randomized clinical study is intended to compare three different modalities of navigation in bronchial tree - virtual bronchoscopy (VBN), radial endobronchial ultrasound (EBUS) and combination of both techniques.

Inclusion Criteria:Patients with newly diagnosed unverified solitary or multiple (up to 3) peripheral pulmonary lesions (PPLs)PPL size 5 - 40 mmActual chest CT scan (<31 days prior to navigation bronchoscopy), collimation 1 mm, pulmonary window, DICOM formatAge > 18 yearsSigned Informed consent formWilling and ability to undergone a navigational bronchoscopyExclusion Criteria:Unability to undergone navigation bronchoscopy for any reasonAny malignant disease during last 36 monthsKnown central endobronchial lesion of any causeHIV-infection