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NCT05741632
Safety Profile Comparison of Undiluted Intracameral Moxifloxacin vs. Levofloxacin in Cataract Surgery
Conditions: Cataract
Sex: All
Ages: 40 Years – 65 Years
Healthy volunteers: 1
Phase: PHASE1
Enrollment: 68
Sponsor: Melva Louisa
Location: Indonesia
Summary
The goal of this randomized clinical trial study is to compare safety profile undiluted intracameral moxifloxacin vs levofloxacin during cataract surgery.
The main question it aims to answer is whether moxifloxacin and levofloxacin have similar safety profile.Participant will be randomized into two treatment arms.
All participant will receive standardized treatment before, during, and after surgery and will be followed up at one day, one week, and one month after surgery.
Eligibility Criteria
Inclusion Criteria:Imature senile cataract in one or both eyeAgree to be included and signed informed consentExclusion Criteria:Have a history of allergy to moxifloxacin or levofloxacin or any other antibioticsOther ocular comorbids such as uveitis, glaucoma, diabetic retinopathy, pseudoexfoliation, and endothelial disordersOcular surgery prior to studySign of infection or inflammation around the eyeCataract density more than grade 4 according to LOCS III gradingCorneal endothelial cell density < 1500 cell/ mm2Anterior chamber depth < 2.5 mmDiabetes mellitus type 2
Source: ClinicalTrials.gov (NCT05741632). StuddyBuddy aggregates publicly available trial information.