Effect of Different Intensities of Repeated Low-Level Red-Light Therapy on Choroidal and Retinal Blood Flow Among Adults

The purpose of this clinical trial is to evaluate the effect of different intensities of repeated low-level red-light (RLRL) therapy on the choroidal and retinal blood flow among adults.

Inclusion Criteria:Aged 18-40 years at enrolment.Healthy adults with best corrected visual acuity equal to or better than 1.0 in both eyes.No other ocular condition except for myopia.Provision of consent and able to participate in all required activities of the study.Exclusion Criteria:Secondary myopia, such as a history of retinopathy of prematurity or neonatal problems, or syndromic myopia with a known genetic disease or connective tissue disorders, such as Stickler or Marfan syndrome.Strabismus and vision abnormalities in either eye.Refractive media opacity: corneal opacities, cataracts, or implanted intraocular lens, etc.Ocular abnormalities that affect retinal function: macular degeneration, diabetic retinopathy, retinal detachment, glaucoma, or ocular hypertension, endophthalmitis, uveitis, optic neuropathy, etc.Previous history of refractive surgery, intraocular surgery, laser therapy, and intravitreal injection, etc.Systemic abnormalities: diabetes, hypertension, etc.Drugs therapies with toxicity effects on the retina: hydroxychloroquine, etc.Other contraindications, including but not limited to ocular or other systemic abnormalities, that the physician may consider inappropriate for enrolment.