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NCT05748067
Minimally Invasive Treatment for Permanent Molars Affected With Molar-incisor Hypomineralization Defects
Conditions: Molar Incisor Hypomineralization
Sex: All
Ages: 6 Years – 16 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 135
Sponsor: King Abdullah University Hospital
Location: Jordan
Summary
In this prospective randomized clinical trial, the is aim to compare the clinical and radiographic success of 3 minimally invasive treatment protocols on permanent first molars affected with MIH over 24 months.
A total of 135 children/molar teeth (N=45 per group) between the ages of 6-16 years with MIH will be recruited at the post-graduate clinics at Jordan University of Science and Technology (JUST).
Eligibility Criteria
Inclusion Criteria:Permanent molars with MIH with the following MIH indices (2a, 2b, 3, 4a, 4b) affected by caries (ICDAS 3 or 4) or post eruptive breakdown.Restorable teethPermanent molars with MIH with NO clinical/radiographic signs and symptoms of irreversible pulpitis or pulpal necrosis.Clear band of dentine radiographically between the carious lesion and the pulp.Exclusion Criteria:Medically compromised patients.Permanent molars with MIH with the following indices (1, 2c, 4c, 0, 1).Permanent molars with MIH with severe post eruptive breakdown therefore, unrestorable.Permanent molars with MIH with clinical/radiographic signs and symptoms of irreversible pulpitis or pulpal necrosis.No clear band of dentine radiographically between the carious lesion and the pulp.
Source: ClinicalTrials.gov (NCT05748067). StuddyBuddy aggregates publicly available trial information.