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NCT05748587
Iron, Alpha-Synuclein, and Lymphocyte-activation Gene-3 in Ischemic Stroke
Conditions: Brain Ischemic Stroke
Sex: All
Ages: 50 Years – 70 Years
Enrollment: 48
Sponsor: Aswan University Hospital
Location: Egypt
Summary
This observational study aims to detect levels of iron, alpha-synuclein, and soluble lymphocyte activation gene 3 in acute ischemic stroke patients.
And to see expressions of iron, alpha-synuclein, and lymphocyte activation gene 3 in the brain tissue of ischemic rats.
The main questions it aims to answer are:Is there an association between iron and alpha-synuclein accumulation in ischemic stroke?Is there any change in soluble lymphocyte activation gene levels in ischemic stroke and if these levels are related to stroke severity and infarction size? .
Can soluble lymphocyte activation gene levels be used as an early biomarker to diagnose ischemic stroke?
Eligibility Criteria
Inclusion Criteria:Patients at the age between 50-70 years.Patients having neurological symptoms of acute ischemic stroke.Exclusion Criteria:Patients with acute hemorrhagic stroke.Patients with Parkinson's disease (PD).Patients with dementia, and Alzheimer's disease.Patients with any type of malignancy.Patients with central nervous system infection.
Source: ClinicalTrials.gov (NCT05748587). StuddyBuddy aggregates publicly available trial information.