Ropivacaine Pharmacokinetics After Erector Spinae Block

Sex: All

Ages: 8 Years – 18 Years

Healthy volunteers: 1

Phase: PHASE4

Enrollment: 46

Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Summary

The primary aim is to evaluate the analgesic efficacy of either technique by measuring cumulative morphine consumption in the first 24 hours after an erector spinae plane block with 2 ml/kg of ropivacaine 0.1% (2 ml/kg) or 1 ml/kg of ropivacaine 0.2%.The secondary aim of this study is to describe the pharmacokinetics of ropivacaine 0.1% and ropivacaine 0.2% after erector spinae block in children undergoing posterior spinal fusion.

Eligibility Criteria

Inclusion Criteria:Patients ≥ 8 year older and > 25 kg undergoing posterior spinal fusion surgeryParents or legal guardians that are fluent in French of EnglishExclusion Criteria:Patients with any contraindication to locoregional anesthesiaPatients that are expected to be intubation for a prolonged period of time after surgeryPatients with anemia (hematocrit < 30%) before surgery or at time of the first study blood drawPatients that do not receive an erector spinae plane blockParents or legal Patient/legal guardian that to not consent to participate in the study

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05755334). StuddyBuddy aggregates publicly available trial information.