Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53

The goal of this observational study is to clarify the significance of TB, PDC, DR, MELF, and immunohistochemical expression of those infiltrative patterns in patients with endometrial carcinomas (EC). The main questions it aims to answer are:What is the relationship between TB, PDC, DR, MELF, and other clinicopathological features of patients with endometrial carcinomas (EC)?What is the association of TB, PDC, DR, and MELF patterns with disease-free survival and overall survival?Will the evaluation of the immunohistochemical expression of P53 in the TB, PDC, DR, and MELF patterns be important?

Inclusion Criteria:Histologically proven Endometrial cancer specimens.underwent total abdominal hysterectomy, with myometrial invasion.Exclusion Criteria:Endometrial biopsieshysterectomy specimens diagnosed with different pathological lesions rather than EC.Specimens with prior chemotherapy or radiotherapy.specimens without myometrial invasion.